Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (C-Term) antibody

Antigen: Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK)

Synonyms: CMG, FGS4, LIN2, TNRC8, CAGH39, MICPCH, FLJ22219, FLJ31914, LIN-2, Pals3, DXPri1, DXRib1, mLin-2, MGC7449

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN359407

Additional Information

Characteristics: Synonyms: Lin-2 homolog, LIN2, Peripheral plasma membrane protein CASK,Calcium/calmodulin-dependent serine protein kinase

Alternative name: CASK

Gene ID: 8573

Swiss-Prot: O14936

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated syntheticpeptide selected from the C-terminal region of human CASK.

Cross-Reactivity: Human, Mouse (Murine)

Isotype: Ig  (Matching secondary antibodies)

Description: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor,generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. Bythis basic mechanism, protein kinases mediate most of the signal transduction ineukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression,cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With morethan 500 gene products, the protein kinase family is one of the largest families of proteinsin eukaryotes. The family has been classified in 8 major groups based on sequencecomparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Thecalcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated byCa2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).

Specificity: This antibody detects Cask at C-term. Species: Human and Mouse. Others not tested. Add. Information: Calculated Molecular weight: 105064 Da

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: PBS with 0.09% (W/V) Sodium Azide as preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only