Prohibitin 2 antibody (N-Term)
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- Target See all Prohibitin 2 (PHB2) Antibodies
- Prohibitin 2 (PHB2)
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Prohibitin 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects REA (PHB2) at N-term.
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHB2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PHB2 Primary Antibody
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anti-Prohibitin 2 (PHB2) antibody
PHB2 Reactivity: Human WB, IHC (p), IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Monoclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 225-255) antibodyPHB2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB15576 unconjugated
anti-Prohibitin 2 (PHB2) (C-Term) antibodyPHB2 Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Dog, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (Middle Region) antibodyPHB2 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 1-299) antibodyPHB2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (AA 197-226), (C-Term) antibodyPHB2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB10631 unconjugated
anti-Prohibitin 2 (PHB2) (AA 106-134) antibodyPHB2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB15314 unconjugated
anti-Prohibitin 2 (PHB2) antibodyPHB2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Prohibitin 2 (PHB2) (Tyr128) antibodyPHB2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Prohibitin 2 (PHB2)
- Alternative Name
- Prohibitin-2 (PHB2 Products)
- Background
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.Synonyms: B-cell receptor-associated protein BAP37, BAP, BAP37, D-prohibitin, PHB2, REA, Repressor of estrogen receptor activity
- Molecular Weight
- 33165 Da
- Gene ID
- 11331, 9606
- UniProt
- Q99623
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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