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Details for Product No. ABIN359558

Casein Kinase 1, alpha 1 (CSNK1A1) (C-Term) antibody

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CK1, CK1a, CKIa, HLCDGP1, PRO2975, 2610208K14Rik, 4632404G05Rik, 5430427P18Rik, Csnk1a, CHUNP6894, ck1alpha, wu:fb65a02, wu:fi30h04, wu:fj19c11, zgc:92158, CKIALPHA, ck1, KER1, CG2028, CK I, CK1alpha, ... show more
»Alternatives C-Term
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN359558
Quantity 0.4 mL
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CK1a.
Specificity This antibody reacts to CK1a.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name Casein kinase I alpha
Background Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.
Alternate names: CK1, CKI-alpha, CSNK1A1
Gene ID 1452
NCBI Accession 9606
UniProt P48729
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50. Flow cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Fish, Cegielska, Getman et al.: "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14875-83, 1995 (PubMed).

Liu, Li, Semenov et al.: "Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism." in: Cell, Vol. 108, Issue 6, pp. 837-47, 2002 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Alternatives for antigen "Casein Kinase 1, alpha 1 (CSNK1A1)", type "Antibodies"
Hosts (53), (18), (1), (1), (1)
Reactivities (75), (40), (38), (13), (12), (2), (1), (1), (1)
Applications (67), (46), (24), (16), (10), (10), (3), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (5), (4), (4), (4), (3), (1), (1), (1), (1), (1)