ITPKA antibody (C-Term)

Catalog No. ABIN360691

This Rabbit Polyclonal antibody specifically detects ITPKA in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ITPKA antibody (C-Term) (ABIN360691)

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPKA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ITPKA Antibody

Binding Specificity: AA 353-382, C-Term

Specificity: This antibody recognizes Human and Mouse ITPKA at C-term.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 353~382 amino acids from the C-terminal region of human ITPKA

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ITPKA

Target: ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))

Alternative Name: ITPKA / IP3 3-Kinase A

Background: ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68 % identical in the C-terminus region.Synonyms: 4, 5-trisphosphate 3-kinase A, IP3KA, Inositol 1, Inositol-trisphosphate 3-kinase A, InsP 3-kinase A

Gene ID: 3706, 9606

UniProt: P23677