LGALS7 antibody

Catalog No. ABIN360888

The Rat Monoclonal anti-LGALS7 antibody (Clone 8J52) (ABIN360888) specifically detects LGALS7 in WB. The antibody is reactive with Mouse samples.

Quick Overview for LGALS7 antibody (ABIN360888)

Target: LGALS7 (Galectin 7 (LGALS7))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LGALS7 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 8J52

Product Details anti-LGALS7 Antibody

Purification: Protein A/G Affinity Chromatography

Sterility: 0.2 μm filtered

Immunogen: Purified Recombinant Mouse Galectin-7 Remarks: Mouse myeloma fused with spleen cells from a Rat

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: 0.2 μm filtered solution in PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LGALS7

Target: LGALS7 (Galectin 7 (LGALS7))

Alternative Name: Galectin-7

Background: Galectins belong to a family of related beta-galactoside-binding lectins, also referred to as S-type or S-Lac lectins. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. Galectin 7 is thought to be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Galectin 7 has been implicated in apoptosis and is believed to upregulate MMP9 and as such be involved in the progression of tumorigenesis. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.Synonyms: Gal-7, HKL-14, LGALS7, LGALS7B, PI7, PIG1, p53-induced gene 1 protein

Gene ID: 10090

UniProt: O54974