IGFBP2 antibody

Catalog No. ABIN360900

The Rat Monoclonal anti-IGFBP2 antibody (Clone 8J27) (ABIN360900) specifically detects IGFBP2 in WB. The antibody is reactive with Mouse samples.

Quick Overview for IGFBP2 antibody (ABIN360900)

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IGFBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 8J27

Product Details anti-IGFBP2 Antibody

Specificity: This antibody detects IGF-BP2. No cross activity to other IGFBPs.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IGF-BP2

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IGFBP2

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Alternative Name: IGFBP2

Background: IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.Synonyms: IBP-2, IBP2, IGF-binding protein 2, IGFBP-2, Insulin-like growth factor-binding protein 2

Gene ID: 16008

NCBI Accession: NP_032368

UniProt: P47877

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation