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Crystallin, alpha A (CRYAA) antibody

Antigen

Crystallin, alpha A (CRYAA)

Synonyms CRYA1, HSPB4, Crya1, lop18, Acry-1, Crya-1, DAcry-1, AI323437, cryaa-A, CRYAA, fc06h04, MGC92036, zgc:92036, wu:fc06h04, alpha-a-crystallin
Clonality Monoclonal (C9f2)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human, Rat (Rattus)

Application
Alternatives ELISA, Western Blotting (WB)
Catalog no. ABIN361018
Quantity 50ul  (1mg/ml)  (Variants)
Price 300.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 10 Business Days

Additional Information

Alternative name a crystallin A
Immunogen Recombinant a crystallin A , Accession / GI number: NP_000385
Isotype IgG8b, k  (Matching secondary antibodies)
Clone C9f2
Description Alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency, which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively. alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They act as molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weight aggregates. These heterogeneous aggregates consist of 30-40 subunits of alpha-crystallins, and the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and the participation in the intracellular architecture.

Application Details

Application Notes Recommended dilution 1:1000
Concentration 1mg/ml
Purification The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Buffer In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Storage Store at -20°, Aliquot to avoid repeated freezing and thawing.
Research Area Hormones, Cytokines
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Crystallin, alpha A (CRYAA)", type "Antibodies"
Hosts Mouse (13), Rabbit (2), Sheep (1)
Reactivities Human (12), Rat (Rattus) (10), Cow (Bovine) (7), Mouse (Murine) (5)
Applications Western Blotting (WB) (14), ELISA (8), Enzyme Immunoassay (EIA) (5), Immunocytochemistry (ICC) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)