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Antibody
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anti-Crystallin alpha B CRYAB
Crystallin, alpha B (CRYAB) antibody
| Antigen |
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| Synonyms |
CRYA2, CTPP2, HSPB5, Crya2, HspB5, Crya-2, AACRYA, CRYAB, DKFZp468D2015, Cryab |
| Clonality |
Monoclonal (2-00E-08) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361020 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 10 Business Days |
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Alternative name
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alpha-Crystallin B
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Immunogen
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Recombinant a-Crystallin B, Accession / GI number: NP_000542
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Isotype
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IgG31b, k (Matching secondary antibodies)
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Clone
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2-00E-08
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Description
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Alpha-Crystallins are composed of two gene products, alpha-Crystallin A and B, for acidic and basic, respectively. alpha-Crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-Crystallin A and B subunits have a 3:1 ratio, respectively. Two additional functions of a-crystallins are an autokinase activity and participation in the intracellular architecture. alpha-Crystallin B is expressed widely in many tissues and organs and occurs in many neurological diseases.
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Application Notes
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Recommended dilution 1:1000
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "Crystallin, alpha B (CRYAB)", type "Antibodies"
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Hosts
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Mouse (46), Rabbit (30), Goat (3)
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Reactivities
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Human (69), Mouse (Murine) (27), Rat (Rattus) (23), Cow (Bovine) (20), Chicken (5), Monkey (1)
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Applications
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Western Blotting (WB) (72), ELISA (25), Immunohistochemistry (IHC) (23), Enzyme Immunoassay (EIA) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Immunofluorescence (IF) (11), Immunocytochemistry (ICC) (5), Flow Cytometry (FACS) (3), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), ELISA (Detection) (1)
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Epitopes
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pSer19 (2), pSer45 (2), pSer59 (2), Ab-19 (1), Ab-45 (1), Ab-59 (1)
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Alternatives 
