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Antibodies
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anti-Synuclein, alpha (SNCA) antibody
Synuclein, alpha (SNCA) antibody
| Antigen |
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| Synonyms |
PD1, NACP, PARK1, PARK4, MGC110988, alphaSYN, MGC105443, snca, MGC64356, SNCA, LOC619283, MGC127560 |
| Clonality |
Monoclonal (5C2) |
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Host
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Reactivity
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Application
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Western Blotting (WB) (99), Immunofluorescence (IF) (59), Enzyme Immunoassay (EIA) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), ELISA (18), Flow Cytometry (FACS) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (12), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (5), Immunoprecipitation (IP) (3), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN361093 |
| Quantity |
50ul (1mg/ml) |
| Price |
331.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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a-Synuclein
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Immunogen
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Recombinant a-Synuclein, Accession / GI number: NP_000336
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Isotype
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IgG2b, kappa chain (Matching secondary antibodies)
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Clone
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5C2
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Description
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Alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques (NAC, amino acids 61-95) is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.
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Application Notes
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Recommended dilution 1:1000
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Hormones, Cytokines
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Restrictions
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For Research Use only
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Alternatives for antigen "Synuclein, alpha (SNCA)", type "Antibodies"
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Hosts
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Rabbit (93), Mouse (46), Sheep (6), Goat (5)
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Reactivities
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Human (131), Rat (Rattus) (73), Mouse (Murine) (67), Cow (Bovine) (3), Dog (Canine) (2), Mammalian (2), Monkey (1)
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Applications
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Western Blotting (WB) (99), Immunofluorescence (IF) (59), Enzyme Immunoassay (EIA) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), ELISA (18), Flow Cytometry (FACS) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (12), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (5), Immunoprecipitation (IP) (3), Dot Blot (Dot) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Biotin (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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pSer129 (10), pTyr133 (7), pTyr136 (7), pTyr125 (6), Ab-125 (5), C-Term (5), Ab-136 (4), aa 61-95 (4), Ab-133 (3)
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Alternatives 
