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Antibodies
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anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) antibody
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) antibody
| Antigen |
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| Synonyms |
PP2CA, MGC9201, FLJ42306, PP2C-ALPHA |
| Clonality |
Monoclonal (P6c7) |
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Host
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Reactivity
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Application
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 Alternatives ELISA, Western Blotting (WB), Immunoprecipitation (IP)
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| Catalog no. |
ABIN361111 |
| Quantity |
50ul (1mg/ml) (Variants) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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PP2C alpha
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Immunogen
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Recombinant PP2Ca, Accession / GI number: NP_808821
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Isotype
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TBD, kappa chain
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Clone
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P6c7
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Description
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Protein phosphatase 2C (PP2C) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM(metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.
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Application Notes
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Recommended dilution 1:250
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Concentration
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1mg/ml
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Purification
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The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Buffer
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In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Storage
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Store at -20°, Aliquot to avoid repeated freezing and thawing.
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Research Area
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Heat Shock Proteins
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Restrictions
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For Research Use only
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Alternatives for antigen "Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)", type "Antibodies"
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Hosts
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Rabbit (8), Mouse (4), Sheep (1)
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Reactivities
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Human (13), Mouse (Murine) (1), Rat (Rattus) (1)
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Applications
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Western Blotting (WB) (15), ELISA (12), Immunohistochemistry (IHC) (4), Immunoprecipitation (IP) (4), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
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Epitopes
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C-Term (1), Center (1), S375 (1), pSer375 (1)
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