2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) antibody

Antigen: 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP)

Synonyms: CNP1, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, CNP, sb:cb662, wu:fd44a05, wu:fi35d08, si:ch73-158e11.4

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine), Human, Rabbit, Rat (Rattus), Sheep (Ovine)

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Catalog no.: ABIN361421

Additional Information

Alternative name: CNP (2,3-cyclic nucleotide-3-phosphodiesterase)

Description: 2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution (Bifulco et al., 2002). It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment (Bifulco et al., 2002, Esposito et al., 2008). Anti-CNP Western blot of rat brain lysate showing the specific immunolabeling of the ~ 46k CNP protein.

Specificity: Specific for the ~ 46k CNP protein in Western blots

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 IHC: 1:1000 (formalin-fixed, Ramaswamy et al. 1990) Quality Control: Western blots performed on each lot.

Purification: Neat serum

Storage: Store at -20 °C, stable for 1 year

Restrictions: For Research Use only

Images

Western blots of rat brain lysate showing the specific immunolabeling of the ~ 46k CNP protein.