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Antibody
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anti-GRP1 General Receptor For phosphoinositides 1-Associated Scaffold Protein GRASP
GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP) antibody
| Antigen |
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| Synonyms |
tamalin, TAMALIN, GRASP |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN361431 |
| Quantity |
100 µl |
| Price |
345.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business days |
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Alternative name
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GRASP
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Format
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Affinity-purified
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Description
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PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). Anti-GRASP Western blot of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein.
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Specificity
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Specific for the ~95k GRASP protein.
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Application Notes
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Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
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Purification
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Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the C-terminal peptide used as antigen.
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Storage
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Store at -20 °C, stable for 1 year
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Restrictions
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For Research Use only
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Alternatives for antigen "GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP)", type "Antibodies"