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Ribosomal S6 Kinase 2 antibody
| Antigen | Ribosomal S6 Kinase 2 |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN361520 |
| Quantity | 100 µl |
| Price | 345.00 $ Plus shipping costs $35.00 |
| Shipping to |
|
| Availability | Ships within 5 to 7 Business Days |
Additional Information
| Format | Affinity-purified |
| Description | The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006). Anti-Ribosomal S6 Kinase Western blot of rat hippocampal lysate showing specific immunolabeling of the ~90k RSK2 protein. |
| Specificity | Specific for the ~90k RSK2 protein. |
Application Details
| Application Notes | Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot. |
| Purification | Prepared from rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as antigen. |
| Storage | Store at -20 °C, stable for 1 year |
| Restrictions | For Research Use only |
