Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) antibody
| Antigen | Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1) |
| Synonyms | htpG |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Rat (Rattus), Mouse (Murine) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC) |
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7 references available |
| Catalog no. | ABIN361822 |
| Quantity |
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| Price | 163.90 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 3 to 4 Business Days |
Additional Information
| Alternative name | Hsp90 |
| Gene ID | 3326 |
| UniProt | P08238 |
| Immunogen | Full length protein Hsp90 |
| Description | Synonyms: Hsp84, Hsp86, Hsp90A, Hsp90AA1, Hsp90AB1, Hsp90B, HspC1, HspC2, HspCAL1, HspCAL4, Hsp90N |
| Characteristics | Accession Number: NP_031381.2 |
| Specificity | Detects ~90kDa proteins corresponding to the molecular mass of Hsp90alpha/beta. |
Application Details
| Application Notes | 1:20000-40000 (ECL) (WB) |
| Purification | Rabbit antiserum |
| Storage | Store at -20° C. Shipping Temperature: Blue Ice or 4° C |
| Storage Shipping Temp Max | Blue Ice or 4 °C |
| Research Area | Heat Shock Proteins, Cancer |
| Restrictions | For Research Use only |
Publications
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Whitesell, Mimnaugh, De Costa et al.: "Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 18, pp. 8324-8, 1994 (PubMed).
Pratt, Toft: "Steroid receptor interactions with heat shock protein and immunophilin chaperones." in: Endocrine reviews, Vol. 18, Issue 3, pp. 306-60, 1997 (PubMed). Pratt: "The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors." in: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), Vol. 217, Issue 4, pp. 420-34, 1998 (PubMed). Pearl, Prodromou: "Structure, function, and mechanism of the Hsp90 molecular chaperone." in: Advances in protein chemistry, Vol. 59, pp. 157-86, 2002 (PubMed). Neckers: "Hsp90 inhibitors as novel cancer chemotherapeutic agents." in: Trends in molecular medicine, Vol. 8, Issue 4 Suppl, pp. S55-61, 2002 (PubMed). Pratt, Toft: "Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery." in: Experimental biology and medicine (Maywood, N.J.), Vol. 228, Issue 2, pp. 111-33, 2003 (PubMed). Arlander, Eapen, Vroman et al.: "Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52572-7, 2003 (PubMed). |
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Alternatives
Alternatives for antigen "Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1)", type "Antibodies"
| Hosts | Rabbit (38), Mouse (25), Rat (3), Chicken (1), Guinea Pig (1) |
| Reactivities | Human (53), Mouse (Murine) (31), Rat (Rattus) (16), Rabbit (11), Chicken (10), Cow (Bovine) (8), Monkey (4), Pig (Porcine) (4), Dog (Canine) (3), Guinea Pig (3), Hamster (2), Sheep (Ovine) (2), Achlya (1), Achlya ambisexualis (1), Cat (Feline) (1), Insect cells (Sf9) (1), Wheat (Triticum) (1) |
| Applications | Western Blotting (WB) (66), Immunohistochemistry (IHC) (28), Immunoprecipitation (IP) (26), ELISA (23), Immunofluorescence (IF) (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Flow Cytometry (FACS) (5), Immunocytochemistry (ICC) (5), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Conjugates | Biotin (1), FITC (1) |
| Epitopes | N-Term (7), C-Term (5), AA 1-732 (2), AA 289-300 (2), AA 604-697 (2), AA 454-524 (1), C-Term,AA 638-667 (1), Internal Region,AA 242-272 (1) |
