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Calnexin (CANX) antibody
| Antigen | Calnexin (CANX) |
| Synonyms |
CNX, P90, IP90, FLJ26570, Cnx, AI988026, D11Ertd153e, 1110069N15Rik, DmelCG11958, CG11958, canx, MGC52927, CANX, PP90, zgc:63524, wu:fe06b12, MGC166317, MGC69400, fj49d10, MGC153946, wu:fj24b04, wu:fj ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human, Monkey, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Guinea Pig, Hamster, Pig (Porcine), Quail, Rabbit, Sheep (Ovine) |
| Application |
Alternatives Western Blotting (WB)
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| Catalog no. | ABIN361827 |
| Quantity | 200uL (Variants) |
| Price | 357.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 to 10 Business Days |
Additional Information
| Alternative name | Calnexin |
| Immunogen | Dog calnexin C-terminal synthetic peptide conjugated to KLH. Identical to human, mouse and rat calnexin sequences over these residues. |
| Format | Antiserum |
| Description | Calnexin, an abundant ~90kDa integral protein of the endoplasmic reticulum, is also referred to as IP90, p88 and p90 (1). It consists of a large 50kDa N-terminal calcium-binding luminal domain, a single transmembrane helix and a short acidic cytoplasmic tail (2, 3). Unlike its ER counterparts which have a KDEL sequence on their C-terminus to ensure ER retention (4), calnexin has positively charged cytosolic residues that do the same thing (3). Most ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into mulitsubunit proteins. Calnexin together with calreticulin, plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglycosylated glycans (5, 6). Calnexin has also been shown to associate with the major histocompatability complex class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin (7). |
| Specificity | Detects ~90kDa. Species cross-reactivity: Human, Monkey, Mouse, Rat, Bovine, Chicken (weak), Dog, guinea Pig, Hamster, Pig, Quail, Rabbit, Sheep, Drosophila (weak), Xenopus (weak). |
| Synonyms | CNX, P90, IP90, FLJ26570, Cnx, AI988026, D11Ertd153e, 1110069N15Rik, DmelCG11958, CG11958, canx, MGC52927, CANX, PP90, zgc:63524, wu:fe06b12, MGC166317, MGC69400, fj49d10, MGC153946, wu:fj24b04, wu:fj49d10, zgc:153946, DKFZp459P042, LOC100283947 |
Application Details
| Application Notes | Recommended dilution for WB 1:2000 |
| Buffer | Antiserum |
| Storage | -20°C, 1 year+, shipped on cold packs or ambient |
| Restrictions | For Research Use only |
Images
| Calnexin CT, rat tissue mix CalnexinCT, mouse colitis, Amplifier SPC108 Anti Calnexin CT, mouse backskin.jpg |
Alternatives
Alternatives for antigen "Calnexin (CANX)", type "Antibodies"
| Hosts | Rabbit (27), Mouse (5), Goat (2) |
| Reactivities | Human (28), Mouse (Murine) (18), Rat (Rattus) (15), Dog (Canine) (14), Cow (Bovine) (9), Guinea Pig (8), Hamster (8), Monkey (8), Pig (Porcine) (8), Rabbit (8), Sheep (Ovine) (8), Chicken (5), Xenopus laevis (4), Quail (3), Mammalian (2) |
| Applications | Western Blotting (WB) (32), ELISA (10), Immunoprecipitation (IP) (9), Immunofluorescence (IF) (8), Enzyme Immunoassay (EIA) (5), Immunohistochemistry (IHC) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Flow Cytometry (FACS) (2), Immunocytochemistry (ICC) (2) |
| Epitopes | AA 50-68 (1), AA 575-593 (1), Ab-583 (1), internal (1), lumenal (1), pSer583 (1) |
