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BCR antibody (pTyr177)

The Rabbit Polyclonal anti-BCR antibody is suitable to detect BCR in samples from Human and Mouse. It has been validated for WB and IHC.

Catalog No. ABIN362225

$240.90

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Quick Overview for BCR antibody (pTyr177) (ABIN362225)

Target

See all BCR Antibodies

BCR (Breakpoint Cluster Region (BCR))

Reactivity

Human, Mouse

Host

Rabbit

Clonality

Polyclonal

Conjugate

This BCR antibody is un-conjugated

Application

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product BCR Primary Antibody

Binding Specificity
30

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4

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3

3

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2

2

1

1

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1

1

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1

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1
pTyr177

Specificity

The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 177.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen

Peptide sequence around phosphorylation site of pTyr177 (P-F-Y (p) -V-N) derived from Human Bcr. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype

IgG
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 2E5 unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 1E11G12 unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) antibody
KD Validated BCR Reactivity: Human WB, FACS Host: Rabbit Monoclonal 24GB6945 unconjugated Recombinant Antibody

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibody
BCR Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-100) antibody
BCR Reactivity: Human, Mouse, Rat WB, IF, FACS, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibody
BCR Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (N-Term) antibody
BCR Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 50-100) antibody
BCR Reactivity: Human ICC, IF/ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

BCR (Breakpoint Cluster Region (BCR))

Alternative Name

Bcr

Background

GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Molecular Weight

210 kDa

NCBI Accession

NP_004318

UniProt

P11274

Pathways

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling