STAT6 antibody (AA 643-647)

Catalog No. ABIN362577

Cited in 1 publication. The Rabbit Polyclonal anti-STAT6 antibody (ABIN362577) specifically detects STAT6 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for STAT6 antibody (AA 643-647) (ABIN362577)

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STAT6 Antibody

Binding Specificity: AA 643-647

Specificity: The antibody detects endogenous level of total STAT6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

Immunogen: Peptide sequence around AA 643-647 (P-A-T-I-K) derived from Human STAT6. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

References for anti-STAT6 antibody (ABIN362577)

Cheng, Wang, Xia, Yan, Tang, Chen, Zhang, Liu, Kong, Sjöberg, Folco, Libby, Liao, Shi: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." in: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).

Target Details for STAT6

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Alternative Name: STAT6

Background: Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Molecular Weight: 110 kDa

NCBI Accession: NP_003144

UniProt: P42226

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response