The antibody detects endogenous level of total MARCKS protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 160-164 (K-K-S-F-K) derived from Human MARCKS. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Background
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.