Klra3 antibody

Catalog No. ABIN371086

This Hamster Monoclonal antibody specifically detects Klra3 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Klra3 antibody (ABIN371086)

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This Klra3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 14B11

Product Details anti-Klra3 Antibody

Specificity: This antibody is specific to an epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants. The antibody stains ~ 90 % of NK1.1+CD3- splenocytes, and ~ 6 % of CD8+ spleen cells from C57BL/6 mice. (Ref.1) The antibody also stains 30-80 % of NK1.1+CD3-splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).

Characteristics: Synonyms: Ly49C, Ly49F, Ly49H, Ly49I, Ly-49H, Ly-49C, Ly-49F, Ly-49I, Klra3, Klra9, Klra8, Klra6, T cellsurface glycoprotein Ly 49C, T cell surface glycoprotein Ly 49F, T cell surface glycoproteinLy 49H, T cell surface glycoprotein Ly 49I, Killer cell lectin-like receptor

Purification: Purified

Isotype: IgG

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Klra3

Target: Klra3 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 3 (Klra3))

Alternative Name: KLRA3

Background: Ly49C, Ly49F, Ly49H and Ly49I are members of the lectin like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.Synonyms: Killer cell lectin-like receptor, Klra3, Klra6, Klra8, Klra9, Ly-49C, Ly-49F, Ly-49H, Ly-49I, Ly49C, Ly49F, Ly49H, Ly49I, T cell surface glycoprotein Ly 49C, T cell surface glycoprotein Ly 49F, T cell surface glycoprotein Ly 49H, T cell surface glycoprotein Ly 49I

Gene ID: 16640

UniProt: Q64329