You are viewing an incomplete version of our website. Please click to reload the website as full version.

LAMP2 antibody (Lysosomal-Associated Membrane Protein 2) (APC)

Details for Product anti-LAMP2 Antibody No. ABIN371200, Supplier: Login to see
Antigen
  • cd107b
  • lamp-2
  • lampb
  • LAMP2
  • lamp2
  • DKFZp459J126
  • LAMP-2
  • LGP-B
  • CD107b
  • Lamp-2
  • Lamp-2a
  • Lamp-2b
  • Lamp-2c
  • Mac3
  • LAMPB
  • LGP110
Reactivity
Mouse (Murine)
245
184
32
24
19
6
Host
Rat
156
125
116
1
Clonality (Clone)
Monoclonal ()
Conjugate
This LAMP2 antibody is conjugated to APC
55
36
29
21
10
10
6
5
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
202
156
99
95
80
72
63
39
39
11
9
8
4
4
2
2
2
2
1
1
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Glycoproteins purified from BALB/c mouse embryo 3T3 cell line. (Ref. 1)
Clone ABL-93
Isotype IgG2a
Specificity This antibody is specific to CD107b/LAMP-2 (Mr 110-120 kDa with a core protein of Mr ~40 kDa).
Characteristics Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
Alternative Name CD107b / LAMP2 (LAMP2 Antibody Abstract)
Background CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.2)Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
Gene ID 16784
UniProt P17047
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Flow Cytometry: < / = 0.2 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Furuta, Yang, Chen et al.: "Differential expression of the lysosome-associated membrane proteins in normal human tissues." in: Archives of biochemistry and biophysics, Vol. 365, Issue 1, pp. 75-82, 1999 (PubMed).

Kannan, Stewart, Bounds et al.: "Lysosome-associated membrane proteins h-LAMP1 (CD107a) and h-LAMP2 (CD107b) are activation-dependent cell surface glycoproteins in human peripheral blood mononuclear cells which mediate cell adhesion ..." in: Cellular immunology, Vol. 171, Issue 1, pp. 10-9, 1996 (PubMed).

Chen, Pan, DSouza et al.: "Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells." in: Archives of biochemistry and biophysics, Vol. 239, Issue 2, pp. 574-86, 1985 (PubMed).

Fukuda: "Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking." in: The Journal of biological chemistry, Vol. 266, Issue 32, pp. 21327-30, 1991 (PubMed).