CD16 antibody (Biotin)

Catalog No. ABIN371542

This Mouse Monoclonal antibody specifically detects CD16 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD16 antibody (Biotin) (ABIN371542)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: GRM1

Product Details anti-CD16 Antibody (Biotin)

Specificity: This antibody recognizes CD16/FcgammaRIII.

Characteristics: Synonyms: CD16a, CD16b, FCG3, FCGR3, IGFR3, FCGR3B, Fc-gamma RIII, FcRIII, Low affinityimmunoglobulin gamma Fc region receptor III

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: 10 μL/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype. CD16 is involved in NK activation and signal transduction. (Ref.1-5)Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gene ID: 2214

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process