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Retinoic Acid Receptor alpha antibody (N-Term)
RARA
Reactivity: Human, Mouse, Cow, Dog
WB
Host: Mouse
Monoclonal
763
unconjugated
Product Details anti-Retinoic Acid Receptor alpha Antibody
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Target
See all Retinoic Acid Receptor alpha (RARA) Antibodies
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Binding Specificity
All epitopes for Retinoic Acid Receptor alpha antibodies
N-Term
Reactivity
All reactivities for Retinoic Acid Receptor alpha antibodies
Human, Mouse, Cow, Dog
Host
All hosts for Retinoic Acid Receptor alpha antibodies
Mouse
Clonality
All clonalities for Retinoic Acid Receptor alpha antibodies
Monoclonal
Conjugate
All conjugates for Retinoic Acid Receptor alpha antibodies
This Retinoic Acid Receptor alpha antibody is un-conjugated
Application
All applications for Retinoic Acid Receptor alpha antibodies
Western Blotting (WB)
Specificity
This antibody is specific for the ~48k RAR-alpha isotype.
Cross-Reactivity (Details)
Species reactivity (expected):Bovine, Canine (Dog) and Mouse. Species reactivity (tested):Human.
Characteristics
Synonyms: NR1B1, Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1
Purification
Prepared from Mouse Ascites by Ammonium Sulfate Precipitation followed by Affinity Chromatography on Protein G.
Immunogen
Peptide corresponding to amino acid residues from the N-terminal region of humanretinoic acid receptor, alpha-isotype.
Clone
763
Isotype
IgG1
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Discover our top product RARA Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target Details for Retinoic Acid Receptor alpha
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Target
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Alternative Name
RAR-alpha / RARA (RARA Products )
Synonyms
NR1B1 antibody, RAR antibody, Nr1b1 antibody, RARalpha1 antibody, rar-alpha antibody, etID309833.12 antibody, rara antibody, rara2a antibody, zRAR antibody, zRAR-alpha antibody, zgc:109797 antibody, nr1b1 antibody, RAR-ALPHA1 antibody, HS-RARa antibody, fj66e06 antibody, rara2b antibody, wu:fj66e06 antibody, retinoic acid receptor alpha antibody, retinoic acid receptor, alpha antibody, retinoic acid receptor, alpha a antibody, retinoic acid receptor alpha L homeolog antibody, retinoic acid receptor, alpha b antibody, RARA antibody, Rara antibody, LOC100136372 antibody, raraa antibody, rara.L antibody, rara antibody, rarab antibody
Background
Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXR-alpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).Synonyms: NR1B1, Nuclear receptor subfamily 1 group B member 1, Retinoic acid receptor alpha
Gene ID
5914
UniProt
P10276
Pathways
Nuclear Receptor Transcription Pathway , Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , S100 Proteins
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