ZMYM2 antibody (AA 1250-1300)

Catalog No. ABIN372247

This Rabbit Polyclonal antibody specifically detects ZMYM2 in WB and IHC (p). It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Chicken, Monkey and Orang-Utan.

Quick Overview for ZMYM2 antibody (AA 1250-1300) (ABIN372247)

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Chicken, Monkey, Orang-Utan

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZMYM2 Antibody

Binding Specificity: AA 1250-1300

Specificity: This antibody recognizes Zinc Finger Protein 198 (ZNF198) (ZMYM2).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chicken, Dog, Monkey, Mouse, Orangutan and RatSpecies reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to the amino acids 1250-1300 of human Zinc finger protein 198.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.1-1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ZMYM2

Target: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Alternative Name: ZMYM2

Background: Zfp198 (zinc finger protein 198, also known as ZNF198 or Zinc finger MYM-type protein 2) is a transcription factor that contains 9 MYM-type zinc fingers. Zfp198 interacts with, and is modified by, SUMO1 and colocalises with PML to nuclear bodies. Zfp198 has also been shown to stabilise the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. A chromosomal translocation resulting in a Zfp198-FGFR1 fusion is associated with stem cell leukemia lymphoma syndrome (SCLL). SCLL usually presents as a lymphoblastic lymphoma in association with a myeloproliferative disorder.Synonyms: FIM, Fused in myeloproliferative disorders protein, RAMP, Rearranged in atypical myeloproliferative disorder protein, ZNF198, Zinc finger MYM-type protein 2, Zinc finger protein 198

Gene ID: 7750

NCBI Accession: NP_001177893

UniProt: Q9UBW7