SLC32A1 antibody (N-Term)

Catalog No. ABIN372740

The Rabbit Polyclonal anti-SLC32A1 antibody is suitable to detect SLC32A1 in samples from Rat, Cow, Dog and Non-Human Primate. It has been validated for WB.

Quick Overview for SLC32A1 antibody (N-Term) (ABIN372740)

Target: SLC32A1 (Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1))

Reactivity: Rat, Cow, Dog, Non-Human Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC32A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC32A1 Antibody

Binding Specificity: N-Term

Specificity: Specific for the the ~53k VGAT protein.

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Canine and non-Human Primate.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of rat Vesicular GABA Amino Acid Transporter (VGAT).

Isotype: IgG

Application Details

Application Notes: Western blotting: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for SLC32A1

Target: SLC32A1 (Solute Carrier Family 32 (GABA Vesicular Transporter), Member 1 (SLC32A1))

Alternative Name: VGAT / SLC32A1

Background: The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).Synonyms: GABA and glycine transporter, Solute carrier family 32 member 1, VIAAT, Vesicular GABA transporter, Vesicular inhibitory amino acid transporter

Gene ID: 100364703

NCBI Accession: NP_113970

UniProt: O35458

Pathways: Proton Transport