ICAM5 antibody (C-Term)

Catalog No. ABIN372797

The Goat Polyclonal anti-ICAM5 antibody is suitable to detect ICAM5 in samples from Human, Mouse and Rat. It has been validated for IHC (p) and EIA.

Quick Overview for ICAM5 antibody (C-Term) (ABIN372797)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This ICAM5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ICAM5 Antibody

Binding Specificity: C-Term

Sequence: c-ESPAEGEVFA IQ

Specificity: Recognizes Intercellular Adhesion Molecule 5 (ICAM5).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine and Porcine.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide from the C-terminus of Human ICAM5 (NP_003250.3).

Isotype: IgG

Application Details

Application Notes: ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Alternative Name: ICAM5

Background: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.Synonyms: ICAM-5, Intercellular Adhesion Molecule 5, TLCN, TLN, Telencephalin

Gene ID: 7087

NCBI Accession: NP_003250

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location