CREB3L4 antibody (C-Term)

Catalog No. ABIN374193

The Goat Polyclonal anti-CREB3L4 antibody (ABIN374193) specifically detects CREB3L4 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CREB3L4 antibody (C-Term) (ABIN374193)

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CREB3L4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CREB3L4 Antibody

Binding Specificity: C-Term

Sequence: C-PSGRIRSVLH ADEM

Specificity: This antibody detects CREB3L4 / AIBZIP at C-term.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_570968.1 Genename: CREB3L4

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 50 kDa band observed in Human Placenta lysate(predicted MW of 40 kDa according to NP_570968). Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Prostate shows strongstaining of cytoplasm in the secretory cells of the gland.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for CREB3L4

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Alternative Name: CREB3L4 / AIBZIP

Background: Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor. AIbZIP is a 395 aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor. It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain. Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells, full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear. AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.Synonyms: Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, CREB4, Cyclic AMP-responsive element-binding protein 3-like protein 4, JAL, Transcript induced in spermiogenesis protein 40, cAMP-responsive element-binding protein 3-like protein 4, hJAL

Gene ID: 148327

NCBI Accession: NP_570968

UniProt: Q8TEY5

Pathways: Thyroid Hormone Synthesis