ABCB9 antibody (C-Term)

Catalog No. ABIN374287

This Goat Polyclonal antibody specifically detects ABCB9 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for ABCB9 antibody (C-Term) (ABIN374287)

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ABCB9 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ABCB9 Antibody

Binding Specificity: C-Term

Sequence: C-GHNEPVANGS HKA

Specificity: This antibody detects ABCB9 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_062570, NP_062571 Genename: ABCB9

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 64000. Immunohistochemistry: 3-5 μg/mL. In paraffin embedded Human Testis shows vesiculatecytoplasm staining of primary spermatocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for ABCB9

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Alternative Name: ABCB9

Background: The membrane associated protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half transporter has not yet been determined, however, this protein may play a role in lysosomes. Alternative splicing of this gene results in three known products which are likely to have different substrate specifications.Synonyms: ATP-binding cassette sub-family B member 9, ATP-binding cassette transporter 9, KIAA1520, TAP-like protein, TAPL

Gene ID: 23457, 9606

UniProt: Q9NP78

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process