F-Box and Leucine-Rich Repeat Protein 2 (FBXL2) (N-Term) antibody

Antigen: F-Box and Leucine-Rich Repeat Protein 2 (FBXL2)

Synonyms: FBL2, FBL3, DKFZp564P0622

Epitope: N-Term

Clonality: Polyclonal

Host: Goat

Reactivity: Cow (Bovine)

Application: Western Blotting (WB)

Catalog no.: ABIN374345

Additional Information

Characteristics: Synonyms: F-box/LRR-repeat protein 2, F-box and leucine-rich repeat protein 2, F-box proteinFBL2/FBL3

Alternative name: FBXL2 / FBL2 / FBL3

Gene ID: 25827

Swiss-Prot: Q9UKC9

Immunogen: Peptide from N Terminus of the protein sequence according to NP_036289. 2Genename: FBXL2AA Sequence: VFSNNDEGLINKK-C

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Rat (Rattus)

Description: FBXL2 is a member of the F-box protein family which is characterized by an approximately40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function inphosphorylation-dependent ubiquitination.

Specificity: This antibody detects FBXL2 / FBL2 / FBL3 at N-term. Species Reactivity: Tested: HumanExpected from sequence similarity: Rat, Dog, Cow

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.3-1.0 µg/ml. Approx 48kDa band observed in Human Brain lysates(calculated MW of 47.1kDa according to NP_036289.2). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.5 mg/ml

Purification: Aff - Purified

Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing. Shelf life: one year from despatch.

Restrictions: For Research Use only