FOXP4 antibody (N-Term)

Catalog No. ABIN374449

This Goat Polyclonal antibody specifically detects FOXP4 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for FOXP4 antibody (N-Term) (ABIN374449)

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXP4 Antibody

Binding Specificity: N-Term

Sequence: C-VESASETIRS APSG

Specificity: This antibody recognizes FOXP4.

Cross-Reactivity (Details): Species reactivity (expected):Human and Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the N Terminus of the protein sequence according to NP_612466.

Application Details

Application Notes: Peptide ELISA: 1/4,000. Western Blot: Detects a band of 75 kDa in HEK293 cells expressing exogenous FOXP4(1/5000 dilution, developed using ECL). No cross-reaction observed with HEK293 cellsexpressing exogenous FOXP2 or FOXP1. Predicted Molecular Weight: 74 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for FOXP4

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Alternative Name: FOXP4 / FKHLA

Background: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. (referenced from Entrez Gene)Synonyms: Fork head-related protein-like A, Forkhead box protein P4

Gene ID: 116113

NCBI Accession: NP_001012426

UniProt: Q8IVH2