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Caveolin-1 antibody (Internal Region)

CAV1 Reactivity: Human, Rat, Mouse, Dog, Pig WB, IF, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374578
  • Target See all Caveolin-1 (CAV1) Antibodies
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Binding Specificity
    • 15
    • 15
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 108
    • 64
    • 50
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog, Pig
    Host
    • 99
    • 12
    • 6
    • 2
    Goat
    Clonality
    • 94
    • 25
    Polyclonal
    Conjugate
    • 83
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caveolin-1 antibody is un-conjugated
    Application
    • 93
    • 38
    • 27
    • 27
    • 26
    • 17
    • 16
    • 16
    • 11
    • 11
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Caveolin-1. No cross-reactivity expected to Caveolin-2 and Caveolin-3.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Porcine.
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Synthetic peptide from Human CAV1 / Caveolin. Peptide with sequence C-DELSEKQVYDAH, from the internal region of Caveolin 1 Genename: CAV1
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    Discover our top product CAV1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Alternative Name
    Caveolin-1 (CAV1 Products)
    Synonyms
    fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody
    Background
    Caveolin 1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade.Synonyms: CAV1
    Gene ID
    857, 9606
    UniProt
    Q03135
    Pathways
    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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