Casein Kinase 1 delta antibody (Internal Region)

Catalog No. ABIN374678

The Goat Polyclonal anti-Casein Kinase 1 delta antibody is suitable to detect Casein Kinase 1 delta in samples from Human, Mouse, Rat and Dog. It has been validated for WB.

Quick Overview for Casein Kinase 1 delta antibody (Internal Region) (ABIN374678)

Target: Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This Casein Kinase 1 delta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Casein Kinase 1 delta Antibody

Binding Specificity: Internal Region

Sequence: C-DREERLRHSR NPATR

Specificity: This antibody reacts to both reported isoforms of Casein kinase I delta.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_001884.2, NP_620693.1

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Casein Kinase 1 delta

Target: Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))

Alternative Name: Casein Kinase I delta

Background: The casein kinase 1 family of protein kinases is common to all eukaryotic cells, although tissue distribution and subcellular localisation may vary between isoforms. Casein kinase 1 delta has been implicated in the regulation of p53. Upregulation of casein kinase 1 delta expression has been reported in Alzheimer's disease hippocampus and its association with tau-containing bodies suggests that it may play a role in the abnormal phosphorylation of tau.Synonyms: CKI-delta, CKId, CSNK1D

Molecular Weight: 47.3 kDa (NP_001884.2)

Gene ID: 1453, 9606

UniProt: P48730

Pathways: Hedgehog Signaling, M Phase