Kallikrein 1 antibody (Internal Region)

Catalog No. ABIN374847

The Goat Polyclonal anti-Kallikrein 1 antibody (ABIN374847) specifically detects Kallikrein 1 in WB. The antibody is reactive with Human samples.

Quick Overview for Kallikrein 1 antibody (Internal Region) (ABIN374847)

Target: Kallikrein 1 (KLK1)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Kallikrein 1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to KLK1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence PNDECKKAHVQK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1 / Kallikrein-1

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. Kallikrein 1 releases the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Low renal synthesis and urinary excretion of tissue kallikrein have been linked to hypertension in animals and humans and the kallikrein-kinin system may be involved in the development or progression of cardiovascular disease.Synonyms: EC 3.4.21.35, KLK-1, Kallikrein1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein

Gene ID: 3816

NCBI Accession: NP_002248

UniProt: P06870

Pathways: Complement System