RAD9A antibody (C-Term)

Catalog No. ABIN374855

The Goat Polyclonal anti-RAD9A antibody is suitable to detect RAD9A in samples from Human, Mouse and Dog. It has been validated for WB and EIA.

Quick Overview for RAD9A antibody (C-Term) (ABIN374855)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reactivity: Human, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This RAD9A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RAD9A Antibody

Binding Specificity: C-Term

Specificity: This antibody recognizes RAD9A.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine (Dog).
Species reactivity (tested):Human.

Purification: Affinity Chromatography

Immunogen: Snythetic peptide (C-QGPSPVLAEDSEGE) from the C-Terminus of Human RAD9A (NP_004575.1) Genename: RAD9A

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Alternative Name: RAD9A

Background: Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.Synonyms: Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, EC=3.1.11.2, RAD-9A

Molecular Weight: 42.5 kDa (NP_004575.1).

Gene ID: 5883, 9606

UniProt: Q99638

Pathways: Positive Regulation of Response to DNA Damage Stimulus