NPEPPS antibody (Internal Region)

Catalog No. ABIN374908

This Goat Polyclonal antibody specifically detects NPEPPS in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NPEPPS antibody (Internal Region) (ABIN374908)

Target: NPEPPS (Aminopeptidase Puromycin Sensitive (NPEPPS))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This NPEPPS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPEPPS Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to MP100 / NPEPPS.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-KRDAESIHQYLLQRK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/4000. Western Blot: 0.2 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NPEPPS

Target: NPEPPS (Aminopeptidase Puromycin Sensitive (NPEPPS))

Alternative Name: NPEPPS

Background: NPEPPS (puromycin-sensitive aminopeptidase) is a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. Studies have suggested that NPEPPS is involved in proteolytic events essential for cell cycle, cell growth and viability. It has recently been identified as a modifier of tau-induced neurodegeneration.Synonyms: PSA, Puromycin-sensitive aminopeptidase

Gene ID: 9520

NCBI Accession: NP_006301

UniProt: P55786