MEPCE antibody (Internal Region)

Catalog No. ABIN374909

The Goat Polyclonal anti-MEPCE antibody is suitable to detect MEPCE in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for MEPCE antibody (Internal Region) (ABIN374909)

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This MEPCE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEPCE Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to MEPCE.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat.

Purification: Affinity chromatography

Immunogen: Peptide with sequence KQQRKFQYGNYCK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MEPCE

Target: MEPCE (Methylphosphate Capping Enzyme (MEPCE))

Alternative Name: MEPCE / BCDIN3

Background: MEPCE belongs to the methyltransferase superfamily and contains one BIN3 domain. It is an S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. MEPCE is expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. It is weakly or not expressed in other tissues.Synonyms: 7SK snRNA methylphosphate capping enzyme, Bicoid-interacting protein 3 homolog, Bin-3 homolog, Bin3 homolog

Gene ID: 56257, 9606

UniProt: Q7L2J0

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection