LHX2 antibody (C-Term)

Catalog No. ABIN374969

The Goat Polyclonal anti-LHX2 antibody has been validated for WB and EIA. It is suitable to detect LHX2 in samples from Human, Mouse, Rat and Dog. There is 1 publication available.

Quick Overview for LHX2 antibody (C-Term) (ABIN374969)

Target: LHX2 (LIM Homeobox 2 (LHX2))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This LHX2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-LHX2 Antibody

Binding Specificity: C-Term

Sequence: C-NLEGHEPHSP SQ

Specificity: This antibody reacts to LHX2 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography

Immunogen: Peptide from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/4000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-LHX2 antibody (ABIN374969)

Mangale, Hirokawa, Satyaki, Gokulchandran, Chikbire, Subramanian, Shetty, Martynoga, Paul, Mai, Li, Flanagan, Tole, Monuki: "Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate." in: Science (New York, N.Y.), Vol. 319, Issue 5861, pp. 304-9, (2008) (PubMed).

Target Details for LHX2

Target: LHX2 (LIM Homeobox 2 (LHX2))

Alternative Name: LHX2

Background: Members of the LIM-homeodomain transcription factor family play critical roles during embryonic development in both vertebrates and invertebrates by controlling processes such as asymmetric cell division, tissue specification and differentiation of specific cell types. Lhx2 functions in the development of several different tissues via mesenchymal-epithelial interactions and regulation of stem/progenitor cells.Synonyms: Homeobox protein LH-2, LH2, LHX2, LIM homeobox protein 2, LIM/homeobox protein Lhx2

Gene ID: 9355

NCBI Accession: NP_004780

UniProt: P50458

Pathways: Tube Formation