Cathepsin K antibody (Internal Region)

Catalog No. ABIN374971

This Goat Polyclonal antibody specifically detects Cathepsin K in WB and EIA. It exhibits reactivity toward Human, Rat, Mouse, Pig, Dog and Cow.It has been mentioned in 1 publication

Quick Overview for Cathepsin K antibody (Internal Region) (ABIN374971)

Target: Cathepsin K (CTSK)

Reactivity: Human, Rat, Mouse, Pig, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Cathepsin K Antibody

Binding Specificity: Internal Region

Sequence: C-KTHRKQYNNK VDE

Specificity: This antibody recognizes Cathepsin K.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Pig, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence from the internal region (near Nterminus) of the protein sequence Genename: CTSK

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Cathepsin K antibody (ABIN374971)

Asagiri, Hirai, Kunigami, Kamano, Gober, Okamoto, Nishikawa, Latz, Golenbock, Aoki, Ohya, Imai, Morishita, Miyazono, Kato, Saftig, Takayanagi: "Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis." in: Science (New York, N.Y.), Vol. 319, Issue 5863, pp. 624-7, (2008) (PubMed).

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: Cathepsin K

Background: Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Gene ID: 1513, 9606

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades