LASS1 antibody (Internal Region)

Catalog No. ABIN375016

This Goat Polyclonal antibody specifically detects LASS1 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for LASS1 antibody (Internal Region) (ABIN375016)

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This LASS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LASS1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody is expected to recognize both reported isoforms of LASS1 (NP_067090.1, NP_937850.1)

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-KDLREYDTAEAQ, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LASS1

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Alternative Name: LASS1

Background: LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing mainly one fatty acid donnor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.Synonyms: LAG1, LAG1 longevity assurance homolog 1, LASS1, Longevity assurance gene 1 protein homolog 1, UOG1

Gene ID: 10715, 9606

UniProt: P27544