FTO antibody (Internal Region)

Catalog No. ABIN375028

This Goat Polyclonal antibody specifically detects FTO in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog and Pig.

Quick Overview for FTO antibody (Internal Region) (ABIN375028)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This FTO antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FTO Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to FTO.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence QQKPDCRPYWEKDD, from the Internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/128000. Western Blot: 0.03 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Alternative Name: FTO

Background: Variants in the FTO (fat mass and obesity associated) gene, encoding for protein, fatso, are associated with increased body mass index and obesity in humans. The precise function of this protein remains to be determined. There are four isoforms produced by alternative splicing (FASTA: FTO isoform 1, 2, 3, and 4).Synonyms: Fat mass and obesity-associated protein, KIAA1752

Gene ID: 26383

NCBI Accession: NP_036066

UniProt: Q8BGW1