FKBP4 antibody (C-Term)

Catalog No. ABIN375084

The Goat Polyclonal anti-FKBP4 antibody (ABIN375084) specifically detects FKBP4 in WB. The antibody is reactive with Human samples.

Quick Overview for FKBP4 antibody (C-Term) (ABIN375084)

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FKBP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP4 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to FKBP4 / FKBP52.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-DHPTDTEMKEEQKSN, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 0.01 - 0.03 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FKBP4

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Alternative Name: FKBP4

Background: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase. It binds to the immunosuppressants FK506 and rapamycin which block distinct steps in intracellular signaling pathways. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.Synonyms: 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP52 protein, FKBP59, HBI, HSP-binding immunophilin, PPIase, Peptidyl-prolyl cis-trans isomerase, Rotamase, p59 protein

Gene ID: 2288

NCBI Accession: NP_002005

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway