Melatonin Receptor 1A antibody (Internal Region)

Catalog No. ABIN375156

The Goat Polyclonal anti-Melatonin Receptor 1A antibody (ABIN375156) specifically detects Melatonin Receptor 1A in WB. The antibody is reactive with Human samples.

Quick Overview for Melatonin Receptor 1A antibody (Internal Region) (ABIN375156)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to MTNR1A.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-SLKYDKLYSSKNS, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A

Background: Melatonin Receptor 1A is a G-protein coupled, 7-transmembrane receptor (GPCR family, subfamily melatonin) that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.Synonyms: MTNR1A, Mel-1A-R, Mel1a melatonin receptor, Melatonin receptor type 1A

Gene ID: 4543, 9606

UniProt: P48039