3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (C-Term) antibody

Antigen: 3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1)

Synonyms: PIP, BPntase, Sal3, MGC93112, MGC82412, BPNT1, MGC126947

Epitope: C-Term

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Western Blotting (WB)

Catalog no.: ABIN375176

Additional Information

Characteristics: Synonyms: 3'(2'), 5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol-1,4-phosphatase

Alternative name: BPNT1

Gene ID: 10380

Swiss-Prot: O95861

Immunogen: Peptide with sequence C-RNYDYYASRVPESIK, from the C Terminus of the protein sequence

Cross-Reactivity: Human

Description: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of amagnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treatmanic depression, acts as an uncompetitive inhibitor of this enzyme. This inhibition ofBPntase may account for lithium-induced nephrotoxicity.

Specificity: This antibody reacts to Bisphosphate 3'-nucleotidase. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat.

Application Details

Application Notes: Peptide ELISA: 1/4000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0,5 mg/ml

Purification: Aff - Purified

Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only