Selectin E (SELE) antibody (Biotin)

Antigen: Selectin E (SELE)

Synonyms: ELAM, ESEL, CD62E, ELAM1, LECAM2, SELE

Clonality: Monoclonal (1-2B6)

Host: Mouse

Reactivity: Human

Conjugate: Biotin

Application: Flow Cytometry (FACS)

Catalog no.: ABIN375453

Additional Information

Alternative name: CD62E/E-selectin

Isotype: IgG1

Clone: 1-2B6

Specificity: Human CD62E/E-selectin CD62E represents the 100-110 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.

Application Details

Application Notes: To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent. Purified (UNLB) antibody conjugate: 10 µ L/10 6 cells, Fluorescein conjugate: 10 µ L/10 6 cells, BIOT conjugate: 10 µ L/10 6 cells, R-phycoerythrin conjugate: <= 1 µ g/10 6 cells, Allophycocyanin Spectral Red conjugate: <= 1 µ g/10 6 cells.

Buffer: The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added. Store at 2-8°C. The fluorescein (FITC) conjugate is supplied as 100

Storage: Store at 2-8°C

Restrictions: For Research Use only