P-Selectin antibody

Catalog No. ABIN7270190

The Rabbit Monoclonal anti-P-Selectin antibody is suitable to detect P-Selectin in samples from Human. It has been validated for WB, IHC and IP.

Quick Overview for P-Selectin antibody (ABIN7270190)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This P-Selectin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-P-Selectin Antibody

Purpose: CD62P/P-selectin Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CD62P/P-selectin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P/P-selectin

Background: This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008],CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL,Blood,Cardiovascular,CDs,Cell Adhesion,Cell Adhesion_Cell Adhesion Molecules,Cell Biology & Developmental Biology,Hematopoietic Progenitors,Immunology & Inflammation,Stem Cells,CD62P/P-selectin

Molecular Weight: 105,140kDa

Gene ID: 6403

UniProt: P16109