CD13 antibody

Catalog No. ABIN380044

This Rat Monoclonal antibody specifically detects CD13 in IHC and IHC (p). It exhibits reactivity toward Mouse.

Quick Overview for CD13 antibody (ABIN380044)

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD13 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ER-BMDM1

Product Details anti-CD13 Antibody

Specificity: The antigen is a 160  kDa membrane associated protein which shows aminopeptidase N activity. It is homologous to the human CD13 marker. Antigen distribution: Isolated Cells: The antigen is present on the majority of isolated dendritic cells of the spleen and lymph node. Over 80 % of thioglycollate elicited peritoneal exudate macrophages also express the ER-BMDM1 related antigen. It is absent from freshly isolated bone marrow cells and blood cells. Tissue Sections: Lymphoid organs: macrophages surrounding small blood vessels, interdigitating cells, subpopulation of macrophages in the T-cell areas, capsular and medullary cord macrophages in lymph nodes. Non-lymphoid organs: subpopulation of macrophages (mainly in connective tissues) and dendrocytes, structures positive for aminopeptidase such as the brush border of the small intestine, bile canaliculi in the liver and tubuli and glomeruli in the kidney or type II pneumocytes in the lung. Kupffer cells are negative. Specificity: Mouse: Mature macrophages. Other species: not tested.

Purification: Affinity purified

Immunogen: Cultured monocytes, day 7

Isotype: IgG2a

Application Details

Application Notes: Approved: IHC, IHC-P (1:200)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for CD13

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Alternative Name: ANPEP / CD13

Background: Name/Gene ID: ANPEP
Subfamily: Metallopeptidase M1
Family: Exopeptidase

Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1

Gene ID: 290

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones