Jumonji Domain Containing 6 (JMJD6) (N-Term) antibody

Antigen: Jumonji Domain Containing 6 (JMJD6)

Synonyms: psr, ptdsr, zfpsr, zgc:66264, PSR, PTDSR, PTDSR1, KIAA0585, BEST:LD22859, L0022859, PS, dPSR, DmelCG5383, CG5383, Ptdsr, PtdSerR, mKIAA0585, D11Ertd195e, 5730436I23Rik, GB15204, JMJD6, MGC128950, jmjd6, DKFZp468K1319

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN387893

Additional Information

Alternative name: JMJD6 (PTDSR)

Gene ID: 360665

UniProt: Q6AYK2

Immunogen: This JMJD6 (PTDSR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human PTDSR.

Isotype: Ig

Description: Other names: JmjC domain-containing protein 6, Jumonji domain-containing protein 6, Protein PTDSR, Jmjd6, Ptdsr,

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This JMJD6 (PTDSR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human PTDSR.

Molecular Weight: 46540 DA

Comments:

Background: Also known as JmjC domain-containing protein 6. This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. It functions in differentiation of multiple tissues during development, and in anti-inflammatory cytokine signaling. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, however, subsequent studies have suggested that the protein may cross-react with a monoclonal antibody that recognizes the phosphatidylserine receptor and does not directly function in the clearance of apoptotic cells.

Synonyms: psr, ptdsr, zfpsr, zgc:66264, PSR, PTDSR, PTDSR1, KIAA0585, BEST:LD22859, L0022859, PS, dPSR, DmelCG5383, CG5383, Ptdsr, PtdSerR, mKIAA0585, D11Ertd195e, 5730436I23Rik, GB15204, JMJD6, MGC128950, jmjd6, DKFZp468K1319

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:250~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Signaling, Protein Modifications, Chromatin

Restrictions: For Research Use only

Images

Western blot analysis of anti-PTDSR (N-term) Pab (ABIN387893) in mouse heart, Hela, and HL60 cell line lysates. PTDSR (N-term)(arrow) was detected using the purified Pab.

Publications

Product: Fadok, Bratton, Rose et al.: "A receptor for phosphatidylserine-specific clearance of apoptotic cells." in: Nature, Vol. 405, Issue 6782, pp. 85-90, 2000 (PubMed).