SETDB1 antibody (C-Term)

Catalog No. ABIN387924

The Rabbit Polyclonal anti-SETDB1 antibody (Clone RB5748) (ABIN387924) specifically detects SETDB1 in WB. The antibody is reactive with Human samples.

Quick Overview for SETDB1 antibody (C-Term) (ABIN387924)

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETDB1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB5748

Product Details anti-SETDB1 Antibody

Binding Specificity: AA 1193-1225, C-Term

Predicted Reactivity: M, X, Zf

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SETDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1193-1225 amino acids from the C-terminal region of human SETDB1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SETDB1

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Alternative Name: SETDB1

Background: The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.

Molecular Weight: 143157

Gene ID: 9869

NCBI Accession: NP_001138887, NP_001230420, NP_036564

UniProt: Q15047