UVRAG antibody (AA 366-398)

Catalog No. ABIN388587

The Rabbit Polyclonal anti-UVRAG antibody (Clone RB10847) (ABIN388587) specifically detects UVRAG in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for UVRAG antibody (AA 366-398) (ABIN388587)

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UVRAG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10847

Product Details anti-UVRAG Antibody

Binding Specificity: AA 366-398

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This UVRAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-398 amino acids from the Central region of human UVRAG.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for UVRAG

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Alternative Name: UVRAG

Background: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Molecular Weight: 78151

Gene ID: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5