Prefoldin Subunit 6 (PFDN6) (N-Term) antibody

Antigen: Prefoldin Subunit 6 (PFDN6)

Synonyms: hke2, ke-2, pfd6, h2-ke2, pfdn6a, 23.m05913

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN389346

Additional Information

Alternative name: PFDN6

Gene ID: 10471

UniProt: O15212

Immunogen: This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13~42 amino acids from the C-terminal region of human PFDN6.

Isotype: Ig

Description: Other names: Prefoldin subunit 6, Protein Ke2, PFDN6, HKE2, PFD6

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13~42 amino acids from the C-terminal region of human PFDN6.

Molecular Weight: 14583 DA

Comments:

Background: PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Stem Cells

Restrictions: For Research Use only

Images

Western blot analysis of anti-PFDN6 Antibody (N-term) (ABIN389346) in CEM cell line lysates (35ug/lane). PFDN6 (arrow) was detected using the purified Pab.

Publications

Product: Vainberg, Lewis, Rommelaere et al.: "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin." in: Cell, Vol. 93, Issue 5, pp. 863-73, 1998 (PubMed).