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ABL1 antibody (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase) (Tyr251)

Details for Product anti-ABL1 Antibody No. ABIN389507, Supplier: Log in to see
Antigen
  • ABL1
  • ABL
  • CABL
  • ABLL
  • cb272
  • JTK7
  • bcr/abl
  • c-ABL
  • p150
  • v-abl
  • AI325092
  • Abl
  • E430008G22Rik
  • c-Abl
  • MTP
Alternatives
anti-Human ABL1 antibody for Immunofluorescence
Epitope
Tyr251
49
47
36
27
27
24
23
19
15
13
13
13
12
12
12
12
12
12
12
12
12
8
8
8
7
7
7
7
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
520
286
232
6
2
1
Host
Rabbit
519
20
Clonality (Clone)
Polyclonal ()
Conjugate
This ABL1 antibody is un-conjugated
31
29
29
16
16
16
15
15
15
15
15
15
15
15
Application
Western Blotting (WB)
324
185
154
150
84
49
45
18
10
6
2
2
1
Supplier
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Immunogen This ABL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL.
Clone RB7354
Isotype Ig
Specificity This ABL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABL (ABL1 Antibody Abstract)
Background ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.
Synonyms: Tyrosine-protein kinase ABL2, Abelson murine leukemia viral oncogene homolog 2, Tyrosine kinase ARG, ABL2, ABLL, ARG,
Molecular Weight 128343 DA
Gene ID 27
UniProt P42684
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cancer, Cell Cycle, Cell Structure
Pathways Apoptosis
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.26 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ABL1 antibody (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase) (Tyr251) (ABIN389507) Western blot analysis of anti-ABL Antibody (Y251) (ABIN389507) in A2058 cell line lys...
Background publications Cao, Leng, Liu et al.: "Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases." in: Biochemistry, Vol. 42, Issue 35, pp. 10348-53, 2003 (PubMed).

Cao, Leng, Kufe: "Catalase activity is regulated by c-Abl and Arg in the oxidative stress response." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 29667-75, 2003 (PubMed).

Kruh, King, Kraus et al.: "A novel human gene closely related to the abl proto-oncogene." in: Science (New York, N.Y.), Vol. 234, Issue 4783, pp. 1545-8, 1987 (PubMed).

Kruh, Perego, Miki et al.: "The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 15, pp. 5802-6, 1990 (PubMed).